Description
CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
960 |
| Alternate Names |
- CD44 antigen
- CD44 molecule (Indian blood group)
- CD44R
- CDw44
- cell surface glycoprotein CD44
- chondroitin sulfate proteoglycan 8
- CSPG8
- ECMR-III
- epican
- Epican
- Extracellular matrix receptor III
- GP90 lymphocyte homing/adhesion receptor
- HCELL
- hematopoietic cell E- and L-selectin ligand
- Heparan sulfate proteoglycan
- Hermes antigen
- homing function and Indian blood group system
- HUTCH-I
- Hyaluronate receptor
- IN
- LHR
- MC56
- MDU2CD44 antigen (homing function and Indian blood group system)
- MDU3CDW44
- MIC4MGC10468
- Pgp1
- PGP-1
- PGP-I
- Phagocytic glycoprotein 1
- Phagocytic glycoprotein I
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