CD41/CD61 Products


Description

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Bioinformatics

Product By Gene ID 3674
Alternate Names
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • CD41 antigen
  • GPalpha IIb
  • ITGAB
  • GPIIb
  • platelet-specific antigen BAK
  • Platelet membrane glycoprotein IIb
  • platelet fibrinogen receptor, alpha subunit
  • CD41
  • GP2Bintegrin alpha-IIb
  • CD41BHPA3
  • GTA
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)

Research Areas for CD41/CD61

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
Cellular Markers
Cytoskeleton Markers
Extracellular Matrix
Immunology
Signal Transduction
Stem Cell Markers

PTMs for CD41/CD61

Learn more about PTMs related to CD41/CD61.

Phosphorylation
Sulphation
Glycosylation
Acetylation
Dephosphorylation
Deglycosylation

Bioinformatics Tool for CD41/CD61

Discover related pathways, diseases and genes to CD41/CD61. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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