CD300a/LMIR1 Products

Antibodies
CD300a/LMIR1 Antibody
CD300a/LMIR1 Antibody
NBP1-84431
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CD300a/LMIR1 Antibody (232612 ...
CD300a/LMIR1 Antibody (232612) [Un...
MAB2640
Species: Hu
Applications: WB, Flow
Host: Rat Monoclonal
CD300a/LMIR1 Antibody
CD300a/LMIR1 Antibody
AF2640
Species: Hu
Applications: WB
Host: Goat Polyclonal
Lysates
CD300a/LMIR1 Overexpression L ...
CD300a/LMIR1 Overexpression Lysate...
H00011314-T01
Species: Hu
Applications: WB
CD300a/LMIR1 Overexpression L ...
CD300a/LMIR1 Overexpression Lysate...
NBP2-07516
Applications: WB
Proteins
CD300a/LMIR1 Recombinant Prot ...
CD300a/LMIR1 Recombinant Protein
H00011314-P01
Species: Hu
Applications: WB, ELISA, PA
CD300a/LMIR1 Recombinant Prot ...
CD300a/LMIR1 Recombinant Protein A...
NBP1-84431PEP
Species: Hu
Applications: AC
CD300a/LMIR1 Recombinant Prot ...
CD300a/LMIR1 Recombinant Protein
NBP2-22749
Species: Hu
Applications: PAGE
RNAi
CD300a/LMIR1 RNAi
CD300a/LMIR1 RNAi
H00011314-R02
Species: Hu

Description

Human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), is a 60kDa transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 11314
Alternate Names
  • CMRF35-H9
  • IgSF12
  • CMRF35-H
  • leukocyte membrane antigen
  • CLM-8
  • CMRF35H leukocyte immunoglobulin-like receptor
  • Inhibitory receptor protein 60
  • CMRF35-like molecule 8
  • Immunoglobulin superfamily member 12
  • CMRF-35H
  • IRC2
  • Irp60
  • IRC1
  • CD300a antigenCMRF35H9
  • IGSF12NK inhibitory receptor
  • CMRF-35-H9CD300 antigen-like family member A
  • CMRF35HIRp60
  • IRC1/IRC2
  • CD300a molecule

Research Areas for CD300a/LMIR1

Find related products by research area and learn more about each of the different research areas below.

Mast Cell Markers

PTMs for CD300a/LMIR1

Learn more about PTMs related to CD300a/LMIR1.

Phosphorylation

Bioinformatics Tool for CD300a/LMIR1

Discover related pathways, diseases and genes to CD300a/LMIR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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