CD21 Products

CD21 Antibody (SC0681)
CD21 Antibody (SC0681)
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
CD21 Antibody
CD21 Antibody
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
CD21 Antibody
CD21 Antibody
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Recombinant Human CD21 Protei ...
Recombinant Human CD21 Protein, CF
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
CD21 Recombinant Protein Anti ...
CD21 Recombinant Protein Antigen
Species: Hu
Applications: AC
CD21 Recombinant Protein Anti ...
CD21 Recombinant Protein Antigen
Species: Hu
Applications: AC


CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.


Entrez Human
Uniprot Human
Product By Gene ID 1380
Alternate Names
  • CD21 antigen
  • Epstein-Barr virus receptor
  • Cr2
  • Complement C3d receptor
  • complement receptor type 2
  • CD21
  • EBV receptor
  • complement component (3d/Epstein Barr virus) receptor 2

Research Areas for CD21

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
CD Markers
Dendritic Cell Markers

Bioinformatics Tool for CD21

Discover related pathways, diseases and genes to CD21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related CD21 Blog Posts

Check out the latest blog posts on CD21.
How to identify B cell subsets using flow cytometry
By Victoria OsinskiUsing flow cytometry to identify B cell subsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified a...    Read more.
CD19: An Undoubted Biomarker for B Cells
CD19 is a cell surface protein member of the large immunoglobulin superfamily that complexes with CD21, CD81, and CD225 in the membrane of mature B-cells. A major function of CD19 is to assemble with the antigen receptor of B-lymphocytes to decrease t...    Read more.
Read more CD21 related blogs.