Cathepsin F Products

Antibodies
Cathepsin F Antibody (237208) ...
Cathepsin F Antibody (237208) [Unc...
MAB2075
Species: Hu
Applications: WB, IHC, IP
Host: Mouse Monoclonal
Cathepsin F Antibody
Cathepsin F Antibody
AF2075
Species: Hu
Applications: WB, IHC, IP
Host: Goat Polyclonal
Cathepsin F Antibody
Cathepsin F Antibody
AF2544
Species: Mu
Applications: WB, IHC, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
Cathepsin F Overexpression Ly ...
Cathepsin F Overexpression Lysate ...
H00008722-T01
Species: Hu
Applications: WB
Proteins
Cathepsin F Recombinant Prote ...
Cathepsin F Recombinant Protein
NBP2-22739
Species: Hu
Applications: PAGE

Description

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Mouse
Product By Gene ID 8722
Alternate Names
  • EC 3.4.22
  • CATSFEC 3.4.22.41
  • cathepsin F

Research Areas for Cathepsin F

Find related products by research area and learn more about each of the different research areas below.

Immunology

PTMs for Cathepsin F

Learn more about PTMs related to Cathepsin F.

Phosphorylation
Phosphorothioation
Glycosylation
Cleavage

Bioinformatics Tool for Cathepsin F

Discover related pathways, diseases and genes to Cathepsin F. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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