CARS Products

Description

CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Bioinformatics

Product By Gene ID	833
Alternate Names	CARS1 CysRS cysteine translase cysteine tRNA ligase 1, cytoplasmic Cysteine--tRNA ligase cysteinyl-tRNA synthetase cysteinyl-tRNA synthetase, cytoplasmic EC 6.1.1 EC 6.1.1.16 MGC:11246

Research Areas for CARS

Find related products by research area and learn more about each of the different research areas below.

Amino Acids, Drugs and other small molecules
Cancer
Signal Transduction