Cadherin-12 Products

Description

CDH12 encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq]

Bioinformatics

Entrez	1010 Human
Uniprot	NP_004052 Human NP_004052.2 Human P55289 Human
Product By Gene ID	1010
Alternate Names	BR-cadherin cadherin 12, type 2 (N-cadherin 2) cadherin-12 FLJ34857 N-cadherin 2 Neural type cadherin 2 neural type, 2 neuronal cadherin 2