Cactin Products

Description

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.

Bioinformatics

Uniprot	Q8WUQ7 Human
Product By Gene ID	58509
Alternate Names	C19orf29 cactin homolog cactin cactin, spliceosome C complex subunit chromosome 19 open reading frame 29 FLJ17482 FLJ59622 fSAPc functional spliceosome-associated protein c NY REN 24 antigen NY-REN-24 antigen NY-REN-24