BRN3A Products

Antibodies
BRN3A Antibody (7B4)
BRN3A Antibody (7B4)
H00005457-M04
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Proteins
BRN3A Partial Recombinant Pro ...
BRN3A Partial Recombinant Protein
H00005457-Q01
Species: Hu
Applications: WB, ELISA, PA
BRN3A Recombinant Protein
BRN3A Recombinant Protein
H00005457-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
BRN3A RNAi
BRN3A RNAi
H00005457-R01
Species: Hu

Description

Brn-3a is a transcription factor belonging to the class IV of POU domain transcription factors. It is expressed throughout the peripheral nervous system but especially in postmitotic sensory neurons of dorsal root ganglia. Brn-3a is known to regulate different genes involved in neuronal differentiation and survival (1). Characterization of Brn-3a suggests potential roles of Brn-3a in the development of retinal ganglion cells and sensory neurons, as well as potential roles in the pituitary gland and the immune system. Brn-3a is expressed in the pituitary gland and in a corticotroph cell line (2). The differentiation of the ND7 neuronal cell line to a nondividing phenotype bearing numerous neurite processes is accompanied by a dramatic increase in the levels of the activating POU family transcription factor Brn-3a and a corresponding fall in the levels of the closely related inhibitory factor Brn-3b. Over expression of Brn-3a in these cells can induce neurite outgrowth and the activation of genes encoding synaptic vesicle proteins in the absence of a differentiation-inducing stimulus (3).

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Product By Gene ID 5457
Alternate Names
  • RDC1
  • POU domain class 4, transcription factor 1
  • Brn-3A
  • Oct-T1
  • Brain-3A
  • Homeobox/POU domain protein RDC-1
  • POU domain, class 4, transcription factor 1
  • Brain-specific homeobox/POU domain protein 3A
  • brn-3A
  • RDC-1
  • BRN3Abrain-3A
  • FLJ13449
  • POU class 4 homeobox 1

PTMs for BRN3A

Learn more about PTMs related to BRN3A.

Phosphorylation
Cleavage
Methylation

Bioinformatics Tool for BRN3A

Discover related pathways, diseases and genes to BRN3A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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