Brk Products

Description

Brk is encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. [provided by RefSeq]

Bioinformatics

Entrez	5753 Human
Uniprot	NM_005975 Human NM_005975. Human NP_005966 Human NP_005966.1 Human Q13882 Human
Product By Gene ID	5753
Alternate Names	Breast tumor kinase BRKprotein-tyrosine kinase 6 EC 2.7.10 EC 2.7.10.2 FLJ42088 protein-tyrosine kinase BRK PTK6 protein tyrosine kinase 6 Tyrosine-protein kinase BRK

Research Areas for Brk

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Protein Kinase