BNIP3L Products

Antibodies
Lysates
BNIP3L Overexpression Lysate
BNIP3L Overexpression Lysate
NBL1-08015
Species: Hu
Applications: WB
Proteins
Recombinant Human BNIP3L GST ...
Recombinant Human BNIP3L GST (N-Te...
H00000665-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
BNIP3L Recombinant Protein An ...
BNIP3L Recombinant Protein Antigen
NBP1-88558PEP
Species: Hu
Applications: AC

Description

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growingsubclass of the Bcl-2 family. A novel BH3 domaincontaining protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X) (Matsushima, M. et al.; Yasuda, M. et al.; Chen, G, et al.).Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Over expression of Bnip3L induces apoptosis (Yasuda, M. et al.; Chen, G, et al.). Bnip3L interacts withand overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3Lis localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues (Matsushima, M. et al.; Yasuda, M. et al.). Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.

Bioinformatics

Entrez Human
Mouse
Bovine
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 665
Alternate Names
  • NIP3-like protein X
  • BNIP3H
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A
  • BNIP3A
  • NIP3L
  • BCL2/adenovirus E1B 19-kd protein-interacting protein 3a
  • Adenovirus E1B19K-binding protein B5
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
  • BNIP3a
  • NIXBCL2/adenovirus E1B 19kD-interacting protein 3-like
  • Nix
  • BCL2/adenovirus E1B 19kDa interacting protein 3-like

Research Areas for BNIP3L

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Hypoxia
p53 Pathway

PTMs for BNIP3L

Learn more about PTMs related to BNIP3L.

Methylation
Phosphorylation
Cleavage
Demethylation
Deacetylation

Bioinformatics Tool for BNIP3L

Discover related pathways, diseases and genes to BNIP3L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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