BMP-9 Products

Antibodies
BMP-9 Antibody (360107) [Unco ...
BMP-9 Antibody (360107) [Unconjuga...
MAB3209
Species: Hu, Mu, Pm
Applications: WB, ELISA(Cap), Neut
Host: Mouse Monoclonal
BMP-9 Antibody [Unconjugated] ...
BMP-9 Antibody [Unconjugated]
AF3209
Species: Hu, Mu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
BMP-9 Antibody - Propeptide
BMP-9 Antibody - Propeptide
AF3879
Species: Hu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
BMP-9 Overexpression Lysate ( ...
BMP-9 Overexpression Lysate (Native)
NBL1-11025
Applications: WB
Proteins
BMP-9 Partial Recombinant Pro ...
BMP-9 Partial Recombinant Protein
H00002658-Q01
Species: Hu
Applications: WB, ELISA, PA
BMP-9 Recombinant Protein
BMP-9 Recombinant Protein
H00002658-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
BMP-9 RNAi
BMP-9 RNAi
H00002658-R01
Species: Hu

Description

Bone Morphogenetic Proteins (BMPs) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species. Mature BMPs are 30-38 kDa proteins that assume a TGF beta like cysteine knot configuration. Unlike TGF beta, BMPs do not form latent complexes with their propeptide counterparts. Most BMPs are homodimers, but bioactive natural heterodimers have been reported. Recently it was found that lovostatin, widely used for lowering cholesterol, also increases bone formation by turning on a gene (bmp2) that promotes local bone formation. BMPs create an environment conducive for bone marrow development by stimulating the production of specific bone matrix proteins and altering stromal cell and osteoclast proliferation. In addition to stimulating ectopic bone and cartilage development, BMPs may be an important factor in the development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis. BMPs also appear to be responsible for normal dorsal/ventral patterning. BMPs are found in tissues that induce bone or cartilage growth, such as demineralized bone and urinary epithelium. Cellular responses to BMP5 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors which play significant roles in BMP binding and signaling. One BMP type II receptor and two BMP type I receptors have been identified.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 2658
Alternate Names
  • growth/differentiation factor 2
  • GDF-2
  • BMP9BMP-9Bone morphogenetic protein 9
  • growth differentiation factor 2

Research Areas for BMP-9

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research

PTMs for BMP-9

Learn more about PTMs related to BMP-9.

Phosphorylation
Cleavage

Bioinformatics Tool for BMP-9

Discover related pathways, diseases and genes to BMP-9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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