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Biotin-geldanamycin Products

Support Products
Biotin-geldanamycin
Biotin-geldanamycin
NB110-81560
Applications: NULL

Description

Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle regulatory kinases (1,2). It induces the inactivation, destabilization and eventual degradation of HIF-1