Bcl3 Products

Antibodies
Bcl3 Antibody
Bcl3 Antibody
NB100-56375
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Bcl3 Antibody
Bcl3 Antibody
NBP2-57127
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Bcl3 Antibody
Bcl3 Antibody
H00000602-D01P
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
ELISA Kits
Human Bcl3 ELISA Kit (Colorim ...
Human Bcl3 ELISA Kit (Colorimetric)
NBP2-69957
Species: Hu
Applications: ELISA
Mouse Bcl3 ELISA Kit (Colorim ...
Mouse Bcl3 ELISA Kit (Colorimetric)
NBP2-69958
Species: Mu
Applications: ELISA
Rat Bcl3 ELISA Kit (Colorimet ...
Rat Bcl3 ELISA Kit (Colorimetric)
NBP2-69956
Species: Rt
Applications: ELISA
Lysates
Bcl3 Knockout HeLa Cell Lysat ...
Bcl3 Knockout HeLa Cell Lysate
NBP2-78436
Species: Hu
Bcl3 Overexpression Lysate
Bcl3 Overexpression Lysate
NBP2-07783
Species: Hu
Applications: WB
Proteins
Recombinant Human Bcl3 Protei ...
Recombinant Human Bcl3 Protein
H00000602-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Bcl3 Recombinant Protein Anti ...
Bcl3 Recombinant Protein Antigen
NBP2-57127PEP
Species: Hu
Applications: AC

Description

The transcriptional coactivator, B-cell lymphoma 3-encoded protein (Bcl3) is a member of the inhibitor of nuclear factor kappaB (NF-kappaB) family. Also a known regulator of NF-kappaB, Bcl-3 plays a critical role in the development of normal immune responses. Specifically, Bcl 3 regulates transcriptional activation of NF-kappa-B target genes, by inhibiting the nuclear translocation of the NF-kappa-B p50 subunit in the cytoplasm and acting as transcriptional activator that promotes transcription of NF-kappa-B target genes in the nucleus.

Bcl-3 also contributes to the regulation of cell proliferation, and influences the survival of T cells when they are activated as a result of an immune response. It also contributes to chronic inflammatory disease states such as osteoarthritis and rheumatoid arthritis, and defects in Bcl3 may lead to B-cell chronic lymphocytic leukemia. Therefore, Bcl3 antibodies can be useful tools for studying autoimmune disease and cancer development.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 602
Alternate Names
  • chronic lymphatic leukemia protein
  • D19S37
  • B-cell lymphoma 3-encoded protein
  • BCL4
  • B-cell lymphoma 3 protein
  • BCL-3
  • B-cell leukemia/lymphoma 3
  • Proto-oncogene BCL3
  • B-cell CLL/lymphoma 3

Research Areas for Bcl3

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Cycle and Replication
Chromatin Research
Immunology
Signal Transduction
Transcription Factors and Regulators

PTMs for Bcl3

Learn more about PTMs related to Bcl3.

Phosphorylation
Methylation

Bioinformatics Tool for Bcl3

Discover related pathways, diseases and genes to Bcl3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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