BAZ2A Products

Antibodies
BAZ2A Antibody
BAZ2A Antibody
H00011176-B01P-50ug
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Lysates
BAZ2A Overexpression Lysate ( ...
BAZ2A Overexpression Lysate (Native)
NBP2-07405
Applications: WB
Proteins
BAZ2A Partial Recombinant Pro ...
BAZ2A Partial Recombinant Protein
H00011176-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
BAZ2A RNAi
BAZ2A RNAi
H00011176-R01
Species: Hu

Description

Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 11176
Alternate Names
  • Tip5
  • TTF-I-interacting protein 5
  • TTF-I interacting peptide 5
  • hWALp3
  • bromodomain adjacent to zinc finger domain protein 2A
  • Transcription termination factor I-interacting protein 5
  • FLJ45876
  • WALp3
  • TIP5FLJ13780
  • KIAA0314FLJ13768
  • DKFZp781B109
  • bromodomain adjacent to zinc finger domain, 2A

PTMs for BAZ2A

Learn more about PTMs related to BAZ2A.

Methylation
Deacetylation
Acetylation
Ribosylation

Bioinformatics Tool for BAZ2A

Discover related pathways, diseases and genes to BAZ2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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