Bassoon Products

Antibodies
Bassoon Antibody (SAP7F407)
Bassoon Antibody (SAP7F407)
NB120-13249
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
Bassoon Antibody
Bassoon Antibody
NBP1-46351
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Goat Polyclonal
Bassoon Antibody
Bassoon Antibody
NBP1-80595
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Bassoon Recombinant Protein A ...
Bassoon Recombinant Protein Antigen
NBP1-80595PEP
Species: Hu
Applications: AC
RNAi
Bassoon RNAi
Bassoon RNAi
H00008927-R01
Species: Hu

Description

Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle (1-3). Bassoon does not belong to any known protein families. It has been found in rat and mouse with sequence identity of the two proteins at 96% (1). The human BASSOON gene has recently been cloned and localized (3). Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains (1). The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntingtin, abnormal amplification of this region can cause late-onset neurodegeneration (1,3). Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors (2). Another presynaptic protein, Piccolo (4) was found to colocalize with Bassoon in cultured hippocampal neurons (1). These observations suggested that they serve specific functions at synaptic junctions and may be involved in organization of the cytoskeleton at the site of neurotransmitter release (1).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Rat
Product By Gene ID 8927
Alternate Names
  • bassoon (presynaptic cytomatrix protein)

PTMs for Bassoon

Learn more about PTMs related to Bassoon.

Nitration
Cleavage
Phosphorylation
Reduction
Dephosphorylation
Prenylation
Ribosylation

Bioinformatics Tool for Bassoon

Discover related pathways, diseases and genes to Bassoon. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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