Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
IRAK-4 is a member of the interleukine-1 receptor-associated kinase (IRAK) family. The IRAK family is implicated in the Toll-like receptor (TLR) and Il-1R signaling pathway (1). Upon phosphorylation, IRAK-4 interacts with IRAK-1, MYD88 and TRAF6 to form a complex, and activate NF-kB and MAPK pathways (2-3). IRAK-4 phosphorylates and activates IRAK-1 at thr387 and is also known to interact with IRAK-1 but not with the other IRAK members. Additionally, like IRAK-1, IRAK-4 possesses an auto and cross-phosphorylation kinase activity (4).
|Product By Gene ID
- EC 18.104.22.168
- Protein BAP28
- EC 22.214.171.124
- BAP28HEAT repeat-containing protein 1
- HEAT repeat containing 1
Research Areas for BAP28
Find related products by research area and learn more about each of the different research areas below.ImmunologyInnate Immunity
Bioinformatics Tool for BAP28
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