BAP28 Products

Description

IRAK-4 is a member of the interleukine-1 receptor-associated kinase (IRAK) family. The IRAK family is implicated in the Toll-like receptor (TLR) and Il-1R signaling pathway (1). Upon phosphorylation, IRAK-4 interacts with IRAK-1, MYD88 and TRAF6 to form a complex, and activate NF-kB and MAPK pathways (2-3). IRAK-4 phosphorylates and activates IRAK-1 at thr387 and is also known to interact with IRAK-1 but not with the other IRAK members. Additionally, like IRAK-1, IRAK-4 possesses an auto and cross-phosphorylation kinase activity (4).

Bioinformatics

Product By Gene ID	55127
Alternate Names	BAP28HEAT repeat-containing protein 1 EC 4.1.1.31 EC 6.3.4.4 FLJ10359 HEAT repeat containing 1 MGC72083 Protein BAP28

Research Areas for BAP28

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity