ATRIP Products

Description

The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	235610 Mouse 301014 Rat 84126 Human
Uniprot	NM_130384 Human Q8WXE1 Human
Product By Gene ID	84126
Alternate Names	AGS1 ATM and Rad3-related-interacting protein ATR interacting protein ATR-interacting protein DKFZp762J2115 FLJ12343 MGC20625 MGC21482 MGC26740

Research Areas for ATRIP

Find related products by research area and learn more about each of the different research areas below.

Cancer
Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair