ATP6V1C2 Products

Description

ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.

Bioinformatics

Entrez	245973 Human
Uniprot	AAH12142.1 Human NM_144583 Human NP_653184 Human
Product By Gene ID	245973
Alternate Names	ATP6C2 ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform 2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C isoform 2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 Vacuolar proton pump subunit C 2 V-ATPase C2 subunit V-ATPase subunit C 2 VMA5 V-type proton ATPase subunit C 2