ATP6V0E2 Products

Description

Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles,clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found inplasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and spermmaturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transportH+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodesan isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component (Blake-Palmer et al., 2007 (PubMed17350184)).(supplied by OMIM)

Bioinformatics

Entrez	155066 Human
Uniprot	NP_001094062 Human
Product By Gene ID	155066
Alternate Names	ATP6V0 ATPase, H+ transporting V0 subunit e2 chromosome 7 open reading frame 32 H+ transporting V0 subunit E isoform 2-like (rat) Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2