Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AP
Description
The protein encoded by the ATP4A gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. (provided by RefSeq)
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human |
| Product By Gene ID |
495 |
| Alternate Names |
- ATP6Agastric H
- ATPase, H+/K+ exchanging, alpha polypeptide
- ATPase, H+/K+ transporting, alpha polypeptide
- EC 3.6.3
- EC 3.6.3.10
- gastric H
- Gastric H(+)/K(+) ATPase subunit alpha
- gastric H+/K+ ATPase alpha subunit
- gastric hydrogen-potassium ATPase
- H(+)-K(+)-ATPase alpha subunit
- K-ATPase alpha subunit
- K-ATPase catalytic subunit
- potassium-transporting ATPase alpha chain 1
- Proton pump
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