Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu, Xp
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, PA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family which play an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS) a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
421 |
| Alternate Names |
- armadillo repeat protein deleted in velo-cardio-facial syndrome
- FLJ35345
- armadillo repeat gene deleted in velocardiofacial syndrome
|
Bioinformatics Tool for ARVCF
Discover related pathways, diseases and genes to ARVCF. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
-Western-Blot-H00000421-M01-img0005.jpg)
-Immunohistochemistry-Paraffin-H00000421-M01-img0004.jpg)
