ARMC8 Products

Description

ARMC8 (armadillo-repeat-containing protein 8) is part of the conserved CTLH protein complex, where it is present as two alternatively spliced forms: ARMC8alpha and ARMC8beta. Studies have indicated that ARMC8alpha promotes protein degradation by both the proteasome-dependent and the vacuole/lysosome-dependent pathways, by interacting directly with the protein to be degraded or by associating with the monoubiquitin-binding protein HRS respectively. (The CTLH complex is also surmised to be involved in microtubule dynamics.)

Bioinformatics

Entrez	25852 Human
Uniprot	NM_014154 Human NM_015396 Human NM_213654 Human NP_054873 Human NP_054873.2 Human Q8IUR7 Human
Product By Gene ID	25852
Alternate Names	armadillo repeat containing 8 armadillo repeat-containing protein 8 DKFZP434A043 HSPC056 MGC10058 MGC4880