ARL6 Products

Description

ARL6 is encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described. [provided by RefSeq]

Bioinformatics

Entrez	84100 Human
Uniprot	NM_177976 Human AAH24239 Human ARL6_HUMAN Human NP_115522 Human Q9H0F7 Human
Product By Gene ID	84100
Alternate Names	MGC32934 ADP-ribosylation factor-like protein 6 RP55 BBS3 Bardet-Biedl syndrome 3 protein ADP-ribosylation factor-like 6

Diseases related to ARL6

Discover more about diseases related to ARL6.

Bardet-biedl Syndrome
Obesity
Polydactyly
Retinal Degeneration
Congenital Abnormality
Retinal Diseases
Hereditary Diseases
Retinitis Pigmentosa
Kidney Diseases
Impaired Cognition
Microphthalmos
Learning Disabilities
Infertility
Hydrocephalus
Eye Abnormalities
Dysplasia
Edema
Nervousness

Pathways for ARL6

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Transport
Localization
Intraflagellar Transport
Intracellular Transport
Cell Proliferation
Protein Targeting
Neurogenesis
Protein Transport
Melanosome Transport
Cell Growth
Pathogenesis
Rna Interference
Epithelial Cell Proliferation
Nuclear Import

Research Areas for ARL6

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Signal Transduction

PTMs for ARL6

Learn more about PTMs related to ARL6.

Ribosylation
Myristoylation

Bioinformatics Tool for ARL6

Discover related pathways, diseases and genes to ARL6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.