ARL2BP Products

Description

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq]

Bioinformatics

Entrez	107566 Mouse 23568 Human
Uniprot	AAH03087 Human NM_012106 Human NP_036238 Human Q9D385 Mouse Q9Y2Y0 Human
Product By Gene ID	23568
Alternate Names	ADP-ribosylation factor-like 2 binding protein ADP-ribosylation factor-like protein 2-binding protein ARF-like 2-binding protein BART1binder of Arl Two BARTArf-like 2 binding protein BART1 Binder of ARF2 protein 1 binder of Arl2

Research Areas for ARL2BP

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Signal Transduction