ARHGEF3 Products

Antibodies
ARHGEF3 Antibody
ARHGEF3 Antibody
NBP1-85130
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ARHGEF3 Antibody
ARHGEF3 Antibody
NBP2-15456
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ARHGEF3 Antibody
ARHGEF3 Antibody
H00050650-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
ARHGEF3 Overexpression Lysate ...
ARHGEF3 Overexpression Lysate (Den...
H00050650-T01
Species: Hu
Applications: WB
ARHGEF3 Overexpression Lysate ...
ARHGEF3 Overexpression Lysate (Nat...
NBL1-07681
Applications: WB
Proteins
Recombinant Human ARHGEF3 Pro ...
Recombinant Human ARHGEF3 Protein
H00050650-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ARHGEF3 Pro ...
Recombinant Human ARHGEF3 Protein
H00050650-P01
Species: Hu
Applications: WB, ELISA, PA
ARHGEF3 Recombinant Protein A ...
ARHGEF3 Recombinant Protein Antigen
NBP1-85130PEP
Species: Hu
Applications: AC
RNAi
ARHGEF3 RNAi
ARHGEF3 RNAi
H00050650-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ARHGEF3, also known as Rho guanine nucleotide exchange factor 3, is a 526 amino acid protein that functions when extracellular interactions activate G coupled protein receptors through conversion of GTP into GDP, by increasing GTPase activity specifically Rho GTPases, which in turn has been shown to have a strong role in bone cells specifically with bone mineral density (BMD). Studies of ARHGEF3 are being done on the following diseases and disorders, hypochromic anemia, osteoporosis, neuronitis, leukemia, arthritis, and spasticity. This protein has interactions with RHOA, RHOB, SHC1, and CDC42 in the G-protein signaling pathways of both RhoA and RhoB, cell death signaling via NRAGE, NRIF and NADE, as well as the interferon pathway.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 50650
Alternate Names
  • FLJ98126
  • Exchange factor found in platelets and leukemic and neuronal tissues
  • DKFZp434F2429
  • RhoGEF protein
  • rho guanine nucleotide exchange factor 3,59.8 kDA protein
  • DKFZP434F2429
  • XPLNXPLN
  • MGC118905
  • Rho guanine nucleotide exchange factor (GEF) 3

Pathways for ARHGEF3

View related products by pathway and learn more about each of the pathways below.

Peristalsis
Platelet Activation
Neurogenesis
Cell Maturation

Research Areas for ARHGEF3

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for ARHGEF3

Discover related pathways, diseases and genes to ARHGEF3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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