Apc7 Products

Antibodies
Apc7 Antibody
Apc7 Antibody
NBP1-40367
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Apc7 Antibody
Apc7 Antibody
NBP1-77379
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Apc7 Antibody
Apc7 Antibody
NBP1-58224
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Apc7 Overexpression Lysate (N ...
Apc7 Overexpression Lysate (Native)
NBP2-07066
Proteins
Apc7 Peptide
Apc7 Peptide
NBP1-77379PEP
Species: Hu
Applications: AC

Description

APC7 (anaphase-promoting complex subunit 7) is a member of the E3 enzyme family. This protein contains TPR repeats and has a molecular weight of approximately 63 kD. The APC7 protein is located in the nucleus during interphase and the centrosome during metaphase/anaphase. This protein probably recruits Cdh1 into the APC complex. The APC7 protein functions with other members of the APC complex as a multisubunit cell cycle ubiquitin ligase, and a regulator of sister chromatid separation by degrading securins. In addition, this protein functions in ubiquitin-dependent cyclin catabolism, metaphase/anaphase transition, and spindle elongation. The APC7 protein comprises one subunit of the anaphase promoting complex including APC1-8, and other probable complex proteins APC9-11, Cdc26, Mnd2, Swm1. The APC complex is inactivated by protein kinase A and is activated by CDC20 and Cdh1. The Poly6113 antibody has been shown to be useful for Western blotting of the human APC7 protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 51434
Alternate Names
  • anaphase-promoting complex subunit 7
  • APC7Cyclosome subunit 7
  • anaphase promoting complex subunit 7

Diseases related to Apc7

Discover more about diseases related to Apc7.

Mental Disorders
Major Depressive Disorder
Mood Disorders
Depressive Disorder
Anhedonia
Stress, Psychological

Pathways for Apc7

View related products by pathway and learn more about each of the pathways below.

Protein Metabolic Process
Cell Proliferation
Response To Stress
Metabolic Process
Cell Growth
Synaptic Transmission
Neurogenesis

Bioinformatics Tool for Apc7

Discover related pathways, diseases and genes to Apc7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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