The protein encoded by the Angiotensin I gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
|Product By Gene ID
- serine (or cysteine) proteinase inhibitor
- angiotensin II
- Serpin A8
- SERPINA8angiotensin I
- alpha-1 antiproteinase, antitrypsin
- angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Bioinformatics Tool for Angiotensin I
Discover related pathways, diseases and genes to Angiotensin I. Need help? Read the Bioinformatics Tool Guide
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