AMPK gamma 1 Products

Description

The 5'-AMP-activated protein kinase (AMPK), a member of the SNF1 (sucrose non-fermentor) kinase family (1), is a heterotrimeric protein comprise of alpha (63 kDa), beta (30 kDa) and gamma (38 kDa) subunits. The alpah subunit is the catalytic subunit, while beta and gamma are non-catalytic subunits (although they have been found to interact with the active subunit in liver). AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (2). AMPK is activated by AMP and can be also regulated by treatment with purified protein phosphatase in vitro (3).

Bioinformatics

Product By Gene ID	5571
Alternate Names	5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase, gamma-1 subunit AMPK gamma 1 AMPK gamma-1 chain AMPK gamma1 AMPK subunit gamma-1 AMPKG AMPKG1 MGC8666 PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Research Areas for AMPK gamma 1

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Cancer
Hypoxia