Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, ICC/IF (-)
Host: Rabbit Polyclonal
WB, ELISA, ICC/IF, IHC, IHC-P, IPHost:
Species: Hu, Mu
Applications: WB, Flow, IHC, IHC-P
Host: Mouse Monoclonal
Applications: Enzyme Activity
Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.
Bioinformatics Tool for Aminoacylase/ACY1
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