Aly Products

Antibodies
Aly Antibody
Aly Antibody
NBP1-33598
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Aly Antibody
Aly Antibody
NBP1-90179
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Aly Antibody (11G5)
Aly Antibody (11G5)
NB100-670
Species: Hu, Xp
Applications: WB, ELISA, ICC/IF, IP, MiAr
Host: Mouse Monoclonal
Proteins
Aly Partial Recombinant Prote ...
Aly Partial Recombinant Protein
H00010189-Q01
Species: Hu
Applications: WB, ELISA, PA
Aly Recombinant Protein Antig ...
Aly Recombinant Protein Antigen
NBP1-90179PEP
Species: Hu
Applications: AC
RNAi
Aly RNAi
Aly RNAi
H00010189-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Pre-mRNA splicing plays an important role in regulation of gene expression. During the splicing process, specific proteins are recruited to the mRNA and assembled into a complex of mRNA-protein near the exon-exon junction. This complex is termed the mRNA-protein complex (mRNP) or the exon-exon junction complex. The proteins that are found in this complex include: Y14, magoh, Aly/REF, RNPS1, Upf3, and DEK.1-5 Aly (also known as mREF1-I) is the mammalian homologue of the yeast mRNA export factor Yra1p.6-7 It is a 233 amino acid RNAbinding protein that contains a RNA-binding domain and is recruited to the mRNP complexes during the splicing. Excess of recombinant expression of Aly in the cells increases both the rate and efficiency of spliced and unspliced mRNA export (in vivo) from the nucleus to the cytoplasm. In contrast to the Y14 protein, Aly is dissociated from the mRNAs after the export to the cytoplasm.1, 5-6

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 10189
Alternate Names
  • Transcriptional coactivator Aly/REF
  • Tho4
  • Ally of AML-1 and LEF-1
  • tho4
  • REF
  • THO complex subunit 4
  • ALY/REF
  • ALYBEFbZIP enhancing factor
  • bZIP-enhancing factor BEF
  • THO complex 4

PTMs for Aly

Learn more about PTMs related to Aly.

Phosphorylation
Methylation

Bioinformatics Tool for Aly

Discover related pathways, diseases and genes to Aly. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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