AlphaA Crystallin/CRYAA Products

AlphaA Crystallin/CRYAA Antib ...
AlphaA Crystallin/CRYAA Antibody (...
Species: Hu
Applications: WB, IHC, IF
Host: Mouse monoclonal
AlphaA Crystallin/CRYAA Antib ...
AlphaA Crystallin/CRYAA Antibody (...
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA
Host: Mouse Monoclonal
AlphaA Crystallin/CRYAA Antib ...
AlphaA Crystallin/CRYAA Antibody
Species: Rt, Bv
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
AlphaA Crystallin/CRYAA Overe ...
AlphaA Crystallin/CRYAA Overexpres...
Applications: WB
AlphaA Crystallin/CRYAA Recom ...
AlphaA Crystallin/CRYAA Recombinan...
Species: Hu
Applications: PAGE


Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index of the lens. The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products--alpha-A and alpha-B. There are at least 5 different proteins comprising the beta-crystallins. The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens. Alpha-Crystallin comprises 40% of total lens protein composition. In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation. It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance. Alpha-B crystallin has been linked to Alexander®s disease where it accumulates in brain cells of those afflicted.


Entrez Human
Uniprot Human
Product By Gene ID 1409
Alternate Names
  • human alphaA-crystallin (CRYA1), 10HspB4
  • CRYA1crystallin, alpha-1
  • HSPB4alpha-crystallin A chain
  • Heat shock protein beta-4
  • crystallin, alpha A

Research Areas for AlphaA Crystallin/CRYAA

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Membrane Trafficking and Chaperones

PTMs for AlphaA Crystallin/CRYAA

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Bioinformatics Tool for AlphaA Crystallin/CRYAA

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