Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins,including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple rolesin different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles andadherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, andsmooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillaractin filaments. This gene encodes a nonmuscle, cytoskeletal, alp
Bioinformatics
| Entrez |
Mouse Rat Human |
| Uniprot |
Human |
| Product By Gene ID |
87 |
| Alternate Names |
- actinin 1 smooth muscle
- actinin, alpha 1
- alpha-actinin 1
- Alpha-actinin cytoskeletal isoform
- alpha-actinin-1
- F-actin cross-linking protein
- FLJ40884
- FLJ54432
- Non-muscle alpha-actinin-1
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