AGPAT2 Products

Description

AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Bioinformatics

Entrez	10555 Human
Uniprot	NM_006412 Human NP_001012745 Human Q5VUD3 Human NP_006403 Human NP_006403.2 Human O15120 Human
Product By Gene ID	10555
Alternate Names	LPAAB EC 2.3.1.51 BSCL1 1-acylglycerol-3-phosphate O-acyltransferase 2 BSCL lysophosphatidic acid acyltransferase-beta LPAAT-beta 1-AGPAT 2,1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acidacyltransferase-beta) 1-AGPAT2,1-AGP acyltransferase 2,1-acyl-sn-glycerol-3-phosphate acyltransferase beta Lysophosphatidic acid acyltransferase beta Berardinelli-Seip congenital lipodystrophy 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acidacyltransferase, beta)

Diseases related to AGPAT2

Discover more about diseases related to AGPAT2.

Lipodystrophy
Familial Generalized Lipodystrophy
Insulin Resistance
Diabetes Mellitus
Myeloid Leukemia, Chronic
Acquired Partial Lipodystrophy
Steatohepatitis
Steatosis
Acanthosis Nigricans
Obesity
Dyslipidemias
Hypertrophy
Malignant Neoplasms
Familial Partial Lipodystrophy
Premature Aging Syndrome
Neoplasms
Hepatomegaly
Diabetes Mellitus, Non-insulin-dependent

Pathways for AGPAT2

View related products by pathway and learn more about each of the pathways below.

Aging
Lipid Homeostasis
Pathogenesis
Transport
Tissue Development
Glycosylation
Adipose Tissue Development
Cell Growth
Angiogenesis
Cell Adhesion
Pigmentation
Reflex
Translation
Wound Healing
Triglyceride Homeostasis
Lipid Transport
Myoblast Differentiation
Cell Proliferation
Insulin Secretion
Localization

PTMs for AGPAT2

Learn more about PTMs related to AGPAT2.

Acylation
Phosphorylation
Glycosylation

Bioinformatics Tool for AGPAT2

Discover related pathways, diseases and genes to AGPAT2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.