AGPAT2 Products

Description

AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Bioinformatics

Entrez	10555 Human
Uniprot	NM_006412 Human NP_001012745 Human NP_006403 Human NP_006403.2 Human O15120 Human Q5VUD3 Human
Product By Gene ID	10555
Alternate Names	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acidacyltransferase, beta) 1-acylglycerol-3-phosphate O-acyltransferase 2 1-AGPAT 2,1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acidacyltransferase-beta) 1-AGPAT2,1-AGP acyltransferase 2,1-acyl-sn-glycerol-3-phosphate acyltransferase beta Berardinelli-Seip congenital lipodystrophy BSCL BSCL1 EC 2.3.1.51 LPAAB LPAAT-beta Lysophosphatidic acid acyltransferase beta lysophosphatidic acid acyltransferase-beta