ACTR1A Products

Antibodies
ACTR1A Antibody
ACTR1A Antibody
NBP2-15274
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ACTR1A Antibody
ACTR1A Antibody
NB100-1423
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
ACTR1A Antibody
ACTR1A Antibody
NBP1-53075
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
ACTR1A Overexpression Lysate ...
ACTR1A Overexpression Lysate (Dena...
H00010121-T01
Species: Hu
Applications: WB
ACTR1A Overexpression Lysate ...
ACTR1A Overexpression Lysate (Native)
NBL1-07285
Applications: WB
Proteins
ACTR1A Partial Recombinant Pr ...
ACTR1A Partial Recombinant Protein
H00010121-Q01
Species: Hu
Applications: WB, ELISA, PA
ACTR1A Recombinant Protein
ACTR1A Recombinant Protein
H00010121-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ACTR1A RNAi
ACTR1A RNAi
H00010121-R01
Species: Hu

Description

The actin-related protein ACTR1A, a member of the superfamily of actin-related proteins, is the major subunit of the dynactin complex, a key component of the cytoplasmic dynein motor machinery. The major components of the dynactin complex, consisting of at least ten polypeptides, include ACTR1A. ACTR1A, the most abundant subunit in the dynactin complex, is most similar to conventional actin (>50% amino acid identity). The dynactin complex has been shown to localize to multiple structures within the cell, including membrane organelles, the centrosome, spindle poles, and spindle pole microtubules during mitosis and prometaphase kinetochores. It regulates dyneinmediated vesicle movement on microtubules as well as spindle assembly and cell division. ACTR1A overexpression in cells results in aberrant spindle morphologies and cell cycle delay at prometaphase, suggesting a possible function of ACTR1A/dynactin complex in progression through the prometaphase of mitosis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 10121
Alternate Names
  • FLJ52800
  • Centractin
  • FLJ52695
  • Actin-RPV
  • ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha)
  • centractin
  • CTRN1
  • alpha-centractin
  • Centrosome-associated actin homolog
  • ARP1actin-RPV
  • FLJ55002
  • ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)

Pathways for ACTR1A

View related products by pathway and learn more about each of the pathways below.

Transport
Cell Migration
Pathogenesis
Localization
Chromatin Remodeling
Rna Splicing

PTMs for ACTR1A

Learn more about PTMs related to ACTR1A.

Phosphorylation

Bioinformatics Tool for ACTR1A

Discover related pathways, diseases and genes to ACTR1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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