ACTL6B Products

Description

The protein encoded by the ACTL6B gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. (provided by RefSeq)

Bioinformatics

Entrez	51412 Human
Uniprot	NM_016188 Human O94805 Human
Product By Gene ID	51412
Alternate Names	53 kDa BRG1-associated factor B actin-like 6 actin-like 6B Actin-related protein Baf53b ACTL6 ArpNalpha arpNalpha BAF53Bactin-like protein 6B BRG1-associated factor 53B hArpN alpha

Research Areas for ACTL6B

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Extracellular Matrix