Acinus Products

Antibodies
Acinus Antibody
Acinus Antibody
NBP1-76869
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, ICC, IF
Host: Rabbit Polyclonal
Acinus Antibody
Acinus Antibody
NBP1-90823
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Acinus Antibody
Acinus Antibody
NBP1-76855
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Proteins
Acinus Partial Recombinant Pr ...
Acinus Partial Recombinant Protein
H00022985-Q01
Species: Hu
Applications: WB, ELISA, PA
Acinus Recombinant Protein An ...
Acinus Recombinant Protein Antigen
NBP1-90823PEP
Species: Hu
Applications: AC
Acinus Peptide
Acinus Peptide
NBP1-76855PEP
Species: Hu
Applications: AC
RNAi
Acinus RNAi
Acinus RNAi
H00022985-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), Acinus S (583 amino acids) and Acinus S; (614 amino acids).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 22985
Alternate Names
  • ACINUS
  • Acinus
  • fSAP152
  • functional spliceosome-associated protein 152
  • apoptotic chromatin condensation inducer in the nucleus
  • KIAA0670DKFZp667N107
  • ACN
  • apoptotic chromatin condensation inducer 1

Research Areas for Acinus

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Chromatin Research
Tumor Suppressors

PTMs for Acinus

Learn more about PTMs related to Acinus.

Cleavage
Phosphorylation
Methylation

Bioinformatics Tool for Acinus

Discover related pathways, diseases and genes to Acinus. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.