ABR Products

Description

ABR encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.

Bioinformatics

Entrez	29 Human
Uniprot	NP_001083 Human NP_068781 Human NP_068781.2 Human Q12979 Human
Product By Gene ID	29
Alternate Names	active breakpoint cluster region-related protein FLJ45954 MDB active BCR-related gene

Diseases related to ABR

Discover more about diseases related to ABR.

Sensorineural Hearing Loss (disorder)
Hearing Problem
Complete Hearing Loss
Acoustic Neuroma
Neoplasms
Noise-induced Hearing Loss
Nervousness
Lymphoma, Non-hodgkin
Conductive Hearing Loss
Neuroma
Presbycusis
Auditory Neuropathy
Otitis Media
Neurilemmoma
Hearing Loss, High-frequency
Vertigo
Ear Inflammation
Hearing Loss, Bilateral

Pathways for ABR

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Reflex
Aging
Pathogenesis
Localization
Cell Death
Transport
Startle Response
Myelination
Regeneration
Prepulse Inhibition
Synaptic Transmission
Secretion
Coagulation
Innervation
Pigmentation
Sulfate Reduction
Lactation
Brain Development
Exocytosis
Echolocation

Research Areas for ABR

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Angiogenesis
Signal Transduction

PTMs for ABR

Learn more about PTMs related to ABR.

Phosphorylation
Reduction
Cleavage
Nitration
Glycosylation
Oxidation
Methylation
Sulphation
Hydroxylation
Amidation

Bioinformatics Tool for ABR

Discover related pathways, diseases and genes to ABR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.