WB, ICC/IF, IPHost:
Hu, Mu, Rt, PmApplications:
WB, ELISA, ICC/IF, IHCHost:
Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.
The Amyloid beta A4 protein (Abeta40) is the more common isoform and is the main components of amyloid plaques. Abeta-40 is produced by cleavage of the Amyloid Precursor Protein (APP) that occurs in the endoplasmic reticulum.
The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.
Abeta40 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.
|Product By Gene ID
- amyloid beta 40
- Beta-amyloid protein 40