ABCD2 Products

Antibodies
ABCD2 Antibody
ABCD2 Antibody
NBP1-33435
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
ABCD2 Antibody
ABCD2 Antibody
NBP2-26123
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
ABCD2 Antibody
ABCD2 Antibody
NBP1-59808
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
ABCD2 Overexpression Lysate ( ...
ABCD2 Overexpression Lysate (Native)
NBL1-07180
Applications: WB
RNAi
ABCD2 RNAi
ABCD2 RNAi
H00000225-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the ABCD2 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily,which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomalABC transporters are half transporters which require a partner half transporter molecule to form a functionalhomodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however thisprotein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. Thisgene has been identified as a candidate for a modifier gene, accounting for the extreme variation amongadrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, agenetically heterogeneous disorder of peroxisomal biogenesis. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 225
Alternate Names
  • ALD1
  • Adrenoleukodystrophy-like 1
  • ALDL1ATP-binding cassette sub-family D member 2
  • ALDRPABC39
  • ALDRhALDR
  • Adrenoleukodystrophy-related protein
  • ATP-binding cassette, sub-family D (ALD), member 2

PTMs for ABCD2

Learn more about PTMs related to ABCD2.

Oxidation
Farnesylation
Glycosylation
Acetylation

Bioinformatics Tool for ABCD2

Discover related pathways, diseases and genes to ABCD2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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