ABCB8 Products

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Bioinformatics

Entrez	11194 Human
Uniprot	NM_007188 Human NP_009119.2 Human Q9NUT2 Human
Product By Gene ID	11194
Alternate Names	ATP-binding cassette, sub-family B (MDR/TAP), member 8 EC 3.6.3 EST328128 M-ABC1mitochondrial ABC protein Mitochondrial ATP-binding cassette 1 mitochondrial