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136R Products

Proteins
Recombinant Viral 136R/Y136 P ...
Recombinant Viral 136R/Y136 Protein
8976-BR
Species: V
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 8976-BR-025/CF
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We have 1 136R Protein

Description

136R, also known as Y136, is an approximately 80 kDa glycosylated and secreted protein encoded by the Yaba-like disease virus genome (1). 136R binds directly to type I and type III interferons (IFN-alpha and IFN-lambda) (1). It prevents the interaction of rhesus and human IFN-alpha as well as human IFN-beta with the IFN-gamma R1 complex, although it shares only 14% amino acid sequence identity with the ECD of human IFN-gamma R1 (1). 136R blocks STAT1 signaling and the anti-viral protective functions of IFN-alpha, -beta, -omega, -kappa, and -lambda 1/IL-29 (1).

Bioinformatics

Alternate Names
  • 136R