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systemic lupus erythematosus

CD80: A co-stimulator of T cell activation

CD80 is a 60kD single chain type I transmembrane glycoprotein that is a member of the immunoglobulin family. CD80 is expressed on activated B- and T-lymphocytes, as well as a subpopulation of previously activated B-cells, but not on the majority of resting B-cells in peripheral blood.

Tags: 
CD86
CD28
CTLA4/CD152
T-cell receptor
systemic lupus erythematosus
B7-1/CD80