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EEA1 antibodies

EEA1 - an early endosome protein important for membrane trafficking

EEA1, or early endosome antigen 1, is a membrane bound Rab5 effector protein specific to the early endosome and plays an important role in membrane trafficking. Early endosomes fuse with endocytic vesicles to redistribute compounds to other cellular destinations. EEA1 contains a C-terminal FYVE domain that binds to phosphatidylinositol-3-phosphate, which targets it to early endosomes [1, 2].