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Bromodeoxyuridine/BrdU

Developmental regulator Daam2 promotes glial cell tumors by degrading Von Hippel-Lindau protein

GFAP expression neuron glia mixed culture ICC

By Jamshed Arslan Pharm.D.

Tags: 
Von Hippel Landau
HIF-1 alpha
Daam2
Neurofibromin 1
PTEN
p53
Bromodeoxyuridine/BrdU
DYKDDDDK Epitope Tag
Myc Epitope Tag
HA Tag

BrDU (Bromodeoxyuridine)

The thymidine synthetic nucleoside analogue bromodeoxyuridine (BrdU) has a long, colorful history of repeated use in molecular and cytokinetic studies, as detailed in reviews by Vanderlaan and Dolbeare (1,2).  Because BrDU is only incorporated into newly synthesized DNA in actively replicating S-phase cells, it allows for accurate and comprehensive quantitation of the pattern, rate, and progression of cell proliferation.

Tags: 
S-phase
proliferation
BrdU antibody
transiently-expressed axonal glycoprotein 1
telomeric repeat-binding factor 2
ataxia telangiectasia mutated
BrdU
Bromodeoxyuridine/BrdU