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alpha Tubulin 4a

Tubulin alpha 4A - A ubiquitous tubulin isoform linked to ALS and infertility

Microtubules are a main component of the cytoskeleton and play essential roles in a variety of cellular processes. These highly dynamic tubular structures are assembled from alpha- and beta-tubulin dimers to form a complex structural network of microtubules throughout the cytoplasm. This network provides a substrate for intracellular trafficking of vesicles, organelles, and other cargo and can also facilitate cell migration. Additionally, during cell division, microtubules make up the mitotic spindle and provide the mechanical force for chromosome segregation.