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Prolyl Hydroxylase 2 Antibody

PHD2: Sensing Cellular Hypoxia

Prolyl-hydroxylase Domain Containing Protein 2 (PHD2) is one of four hydroxylase enzymes that function as oxygen sensors. They are responsible for the post-translational modification of hypoxia-inducible factor 1 alpha (HIF-1 alpha), a component of the transcriptional complex involved in oxygen homeostasis.