Huntingtons

Prostate specific membrane antigen (PSMA), also known as Glutamate carboxypeptidase II (GCPII), is a type II transmembrane glycoprotein that belongs to the M28 peptidase family. It acts as a glutamate carboxypeptidase on different substrates such as folate as well as the neuropeptide N-acetyl-l-aspartyl-l-glutamate. PSMA is expressed in a number of tissues including prostate, kidney, and both the central and peripheral nervous systems.

Huntington's disease is an inherited progressive neurodegenerative disorder which impairs cognition, causes issues with movement, and has associated behavioral changes and emotional problems. There is currently no cure for Huntington's disease, but research is focused on understanding the function of the Huntington's disease gene. Learn more in our infographic below.