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Endoplasmic Reticulum-associated Interferon-inducible

Viperin: A Cellular Inhibitor of DNA and RNA Viruses

Viperin (Virus Inhibitory Protein, Endoplasmic Reticulum-associated, Interferon-inducible) inhibits the replication of a broad spectrum of viruses by several diverse mechanisms. The protein was first identified in 2001, when it was found to be the product of an IFN gamma-inducible gene (1).