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Novus has recently added a new antibody against the terminal deoxynucleotidyl transferase (TdT). This DNA polymerase is expressed in many pre-B and pre-T cells as well as related hematological cancers. Unlike most other DNA polymerases, it does not require a template and catalyzes the addition of nucleotides to the 3’ terminus of DNA. Browse our new products for 2014 to see if this product or any other antibodies can help your research!
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Heart failure has been a... |
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Although autophagy is characterized as a survival response, it may also function as a mechanism of programmed cell death. Researchers have demonstrated that hypoxia-induced autophagy is part of a general mechanism of cell survival that is controlled by HIF-1, and that the expression of both BNIP3 and BNIP3L is required for the optimal induction of autophagy in hypoxia. |
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Dear Researchers, Autophagy plays a critical role in many basic physiological processes as well as in the pathogenesis of various diseases, including cancer. Please visit our Research Area of the Month page and see how Novus’ following antibody tools can help your investigation on an interesting and important question: Autophagy and Cancer: Friend or Foe?
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SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT. MCT1 is a novel gene that was identified from T-cell leukemia/lymphoma cell lines with limited homology to a region of Cyclin H. MCT1 is novel candidate oncogene that results in a shortened G1 phase and increased rate of proliferation. Novus Biologicals has... |
